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The "Current" date suggests when new information and facts was most a short while ago included to this information. In the full short article, the most recent information is highlighted in yellow.This is certainly an open-access article distributed under the terms from the Inventive Commons Attribution-NonCommercial four.0 International License ()

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Taken collectively, PEA and its congeners could signify an revolutionary therapeutic strategy while in the administration of combined neuropathies.‐acylethanolamines (NAEs), endogenous biologically Energetic lipids including the endogenous cannabinoid receptor ligand anandamide along with the satiety variable oleoylethanolamide. PEA was identifie

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PPAR‐α is usually a nuclear receptor protein that belongs into the family members of PPARs and acts as transcription factor regulating gene expression (Issemann and Green, 1990).Costa and colleagues [178] have advised that PEA was able to reduce mechanical allodynia and thermal hyperalgesia following sciatic nerve constriction in mice, via an mo

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